Electron Microscopy

The Electron Microscopy Core Facility is part of the Innovative Electron Microscopy Department. It ensures day-to-day operation of the electron microscopy facility and provides service to researchers at INM covering a large spectrum of electron microscopy techniques (from sample preparation to image analysis) on a broad variety of samples (from hard hybrid materials to soft hydrogels). The core facility team performs the experiments, assists researchers with their use of the facility equipment, provides training for users, and consults regarding best practices for electron microscopy sample preparation, imaging techniques and image processing.

The Service Group works in close cooperation with different research departments at INM, research groups of Saarland University and other institutions on the Campus. The Service Group is also involved in method development at the Innovative Electron Microscopy Department.

Head of Electron Microscopy

This position is currently vacant.
Please take a look at our job posting

Team Members
Phone: +49 (0)681-9300-135
Phone: +49 (0)681-9300-247
Analysis techniques

Analysis techniques offered by the Electron Microscopy Service group:

  • Scanning Electron Microscopy
  • Environmental Scanning Electron Microscopy
  • Focused Ion Beam microscopy and tomography
  • Conventional Transmission Electron Microscopy
  • Transmission Electron Microscopy at cryogenic temperatures
  • X-ray Energy Dispersive Spectroscopy
  • Electron Energy Loss Spectroscopy
  • Electron Backscatter Diffraction
Sample preparation techniques
  • Scanning Electron Microscopy
  • Environmental Scanning Electron Microscopy
  • Focused Ion Beam microscopy and tomography
  • Conventional Transmission Electron Microscopy
  • Transmission Electron Microscopy at cryogenic temperatures
  • X-ray Energy Dispersive Spectroscopy
  • Electron Energy Loss Spectroscopy
  • Electron Backscatter Diffraction

Publications

2025
Nanoparticle shape is the game-changer for blood–brain barrier crossing and delivery through tunneling nanotubes among glioblastoma cells

Sierri, Giulia | Saenz-de-Santa-Maria, Ines | Renda, Antonio | Koch, Marcus | Sommi, Patrizia | Anselmi-Tamburini, Umberto | Mauri, Mario | D'Aloia, Alessia | Creiani, Michela | Salerno, Domenico | Mantegazza, Francesco | Zurzolo, Chiara | Re, Francesca

Nanoscale , 2025, 17 992-1006.
https://pubs.rsc.org/en/content/articlelanding/2024/nr/d4nr03174a

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2024
Actin-templated Structures: Nature's Way to Hierarchical Surface Patterns (Gecko's Setae as Case Study)

Kasper, Jennifer Y. | Laschke, Matthias W. | Koch, Marcus | Alibardi, Lorenzo | Magin, Thomas M. | Niessen, Carien M. | del Campo, Aránzazu

Advanced Science , 2024, 11 (10), 2303816.
https://onlinelibrary.wiley.com/doi/full/10.1002/advs.202303816

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Chitosan/Nanohydroxyapatite/Hydroxyethyl-cellulose-based printable formulations for local alendronate drug delivery in osteoporosis treatment

Afra, Simindokht | Koch, Marcus | Zur-Pinska, Joanna | Dolatshahi, Maryam | Reza Bahrami, Ahmad | Es Sayed, Julien | Moradi, Ali | Matin, Maryam M. | Wlodarczyk-Biegun, Malgorzata K.

2024, 7 100418.
https://www.sciencedirect.com/science/article/pii/S266689392300138X

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A cell-free, biomimetic hydrogel based on probiotic membrane vesicles ameliorates wound healing

Kuhn, Thomas | Aljohmani, Ahmad | Frank, Nicolas | Zielke, Lina | Mehanny, Mina | Laschke, Matthias W. | Koch, Marcus | Hoppstädter, Jessica | Kiemer, Alexandra K. | Yildiz, Daniela | Fuhrmann, Gregor

Journal of Controlled Release , 2024, 365 969-980.
https://www.sciencedirect.com/science/article/pii/S0168365923007952

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Water-Driven Sol-Gel Transition in Native Cellulose/1-Ethyl-3-methylimidazolium Acetate Solutions

Mohamed Yunus, Roshan Akdar | Koch, Marcus | Dieudonné-George, Philippe | Truzzolillo, Domenico | Colgy, Ralph H. | Parisi, Daniele

ACS Macro Letters , 2024, 13 (2), 219-226.
https://pubs.acs.org/doi/10.1021/acsmacrolett.3c00710

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Data-driven analysis of surface roughness influence on weld quality and defect formation in laser welding of Cu–Al

Norouzian, Mohammadhossein | Elahi, Mahdi Amne | Koch, Marcus | Mahin Zaeem, Reza | Kedziora, Slawomir

Proceedings of the Institution of Mechanical Engineers, Part L: Journal of Materials: Design and Applications , 2024, 238 (12), 2471–2486.
https://journals.sagepub.com/doi/10.1177/14644207241236138

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Biodegradable SPI-based hydrogel for controlled release of nanomedicines: A potential approach against brain tumors recurrence

Viale, Francesca | Ciprandi, Matilde | Leoni, Luca | Sierri, Giulia | Renda, Antonio | Barbugian, Federica | Koch, Marcus | Sesana, Silvia | Salvioni, Lucia | Colombo, Miriam | Mantegazza, Francesco | Russo, Laura | Re, Francesca

Journal of Drug Delivery Science and Technology , 2024, 96 105672.
https://www.sciencedirect.com/science/article/pii/S1773224724003411

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Structure–Property Relationships of Granular Hybrid Hydrogels Formed through Polyelectrolyte Complexation

Es Sayed, Julien | Mukherjee, Adrivit | El Aani, Siham | Vengallur, Nayan | Koch, Marcus | Giuntoli, Andrea | Kamperman, Marleen

Macromolecules , 2024, 57 (7), 3190-3201.
https://doi.org/10.1021/acs.macromol.3c02335

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Targeting Intracellular Bacteria with Dual Drug-loaded Lactoferrin Nanoparticles

Andima, Moses | Boese, Annette | Paul, Pascal | Koch, Marcus | Loretz, Brigitta | Lehr, Claus-Michael

ACS Infectious Diseases , 2024, 10 (5), 1696–1710.
https://pubs.acs.org/doi/full/10.1021/acsinfecdis.4c00045

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Towards controlled and simple design of non-enzymatic amperometric sensor for glycerol determination in yeast fermentation medium

Zolotukhina, Ekaterina V. | Butyrskaya, Elena | Fink-Straube, Claudia | Koch, Marcus | Silina, Yuliya E.

Analyticcal and bioanalytical chemistry , 2024, 416 3619-3630.
https://link.springer.com/article/10.1007/s00216-024-05316-7

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