Electron Microscopy

The service group Electron Microscopy covers electron optical and X-ray analytical investigations for all research departements of INM, research groups of the Saarland University of Saarland and external partners. For nanoscale microscopic investigations, transmission electron (TEM) and scanning electron microscopy (SEM) coupled with X-ray spectral analysis is used. TEM lamellae of a wide variety of samples are prepared inside with a focused ion beam (FIB) microscope and further thinned by focussed Argon ion beam (Nanomill) for atomic analytical analysis. Other preparation techniques such as microtomy, electrolytical polishing, ion milling with non-focusing ion beam and sputter coating are also available.

Team Members

Publications

2024
Nanostructured lipid carrier formulation for delivering poorly water-soluble ITF3756 HDAC inhibitor

Kravicz, Marcelo | Taiarol, Lorenzo | Viegas, Juliana S.R. | Sierri, Giulia | Mauri, Michele | Koch, Marcus | Steinkühler, Christian | Re, Francesca

Journal of Drug Delivery Science and Technology , 2024, 101 106238.
https://www.sciencedirect.com/science/article/pii/S1773224724009079#appsec1

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Amine-containing block copolymers for efficient catalyst-free hydroamination and preparation of functional metallopolymers

Rittner, Till | Ghulam, Kinza | Koch, Marcus | Gallei, Marcus

Polymer Chemistry , 2024, 15 (35), 3519-3528.
https://pubs.rsc.org/en/content/articlelanding/2024/py/d4py00780h

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Quantum Sensing Unravels Antioxidant Efficacy Within PCL/Matrigel Skin Equivalents

Wu, Xixi | Koch, Marcus | Perona Martínez, Felipe P. | Schirhagl, Romana | Wlodarczyk-Biegun, Malgorzata K.

Small , 2024, xxxx (xxxx), xxxx.
https://onlinelibrary.wiley.com/doi/10.1002/smll.202403729

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Nominal CaAl2Pt2 and Ca2Al3Pt – two new Intermetallic Compounds in the Ternary System Ca−Al−Pt

Engel, Stefan | Koch, Marcus | Janka, Oliver

Zeitschrift Für Anorganische Und Allgemeine Chemie , 2024, 650 (18), e202400094.
https://onlinelibrary.wiley.com/doi/10.1002/zaac.202400094?af=R

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Design and Self-Assembly of Second-Generation Dendrimer-like Block Copolymers

Hartmann, Frank | Dockhorn, Ron | Pusse, Sebastian | Niebuur, Bart-Jan | Koch, Marcus | Kraus, Tobias | Schießer, Alexander | Balzer, Bizan N. | Gallei, Marcus

Macromolecules , 2024, 57 (15), 7098–7111.
https://pubs.acs.org/doi/10.1021/acs.macromol.4c00944#_i24

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The RNA binding protein IGF2BP2/IMP2 alters the cargo of cancer cell-derived extracellular vesicles supporting tumor-associated macrophages

Mashayekhi, Vida | Schomisch, Annika | Rasheed, Sari | Aparicio-Puerta, Ernesto | Risch, Timo | Yildiz, Daniela | Koch, Marcus | Both, Simon | Ludwig, Nicole | Legroux, Thierry M. | Keller, Andreas | Müller, Rolf | Fuhrmann, Gregor | Hoppstädter, Jessica | Kiemer, Alexandra K.

2024, 22 344.
https://biosignaling.biomedcentral.com/articles/10.1186/s12964-024-01701-y

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A New Class of Polyion Complex Vesicles (PIC-somes) to Improve Antimicrobial Activity of Tobramycin in Pseudomonas Aeruginosa Biofilms

Yildirim, Turgay | Bali, Aghiad | Koch, Marcus | Paul, Pascal | Latta, Lorenz | Scheider-Daum, Nicole | Gallei, Markus | Lehr, Claus-Michael

Small , 2024, 20 (40), 2401926.
https://onlinelibrary.wiley.com/doi/full/10.1002/smll.202401926

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Mechanistic aspects of glycerol oxidation on palladium electrocatalysts in model aqueous and fermentation media solutions

Silina, Yulia E. | Butyrskaya, E. V. | Koch, Marcus | Fink-Straube, Claudia | Korkmaz, Nuriye | Levchenko, M. G. | Zolotukhina, E. V.

Electrochimica Acta , 2024, 497 144479.
https://www.sciencedirect.com/science/article/pii/S0013468624007205?dgcid=rss_sd_all

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Melt electrowritten poly-lactic acid /nanodiamond scaffolds towards wound-healing patches

Wu, Xixi | Li, Wenjian | Herlah, Lara | Koch, Marcus | Wang, Hui | Schirhagl, Romana | Włodarczyk-Biegun

Materials Today Bio , 2024, 26 101112.
https://www.sciencedirect.com/science/article/pii/S2590006424001716

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Evaluation of the Transport and Binding of Dopamine-Loaded PLGA Nanoparticles for the Treatment of Parkinson’s Disease Using In Vitro Model Systems

Danz, Karin | Fleddermann, Jana | Koch, Marcus | Fecioru, Elena | Maahs, Lorenz | Kinsinger, Nicole | Krämer, Johannes | Kraegeloh, Annette | Wagner, Sylvia

Pharmaceutics , 2024, 16 (5), 571_1-15.
https://www.mdpi.com/journal/pharmaceutics

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