Electron Microscopy

The service group Electron Microscopy covers electron optical and X-ray analytical investigations for all research departements of INM, research groups of the Saarland University of Saarland and external partners. For nanoscale microscopic investigations, transmission electron (TEM) and scanning electron microscopy (SEM) coupled with X-ray spectral analysis is used. TEM lamellae of a wide variety of samples are prepared inside with a focused ion beam (FIB) microscope and further thinned by focussed Argon ion beam (Nanomill) for atomic analytical analysis. Other preparation techniques such as microtomy, electrolytical polishing, ion milling with non-focusing ion beam and sputter coating are also available.

Team Members

Publications

2024
Soft Synthetic Cells with Mobile Membrane Ligands for Ex Vivo Expansion of Therapy-Relevant T Cell Phenotypes

Burgstaller, Anna | Piernitzki, Nils | Küchler, Nadja | Koch, Marcus | Kister, Thomas | Eichler, Hermann | Kraus, Tobias | Schwarz, Eva C. | Dustin, Michael | Lautenschlaeger, Franziska | Staufer, Oskar

Small , 2024, 20 (37), 2401844.
https://onlinelibrary.wiley.com/doi/10.1002/smll.202401844

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Towards controlled and simple design of non-enzymatic amperometric sensor for glycerol determination in yeast fermentation medium

Zolotukhina, Ekaterina V. | Butyrskaya, Elena | Fink-Straube, Claudia | Koch, Marcus | Silina, Yuliya E.

Analyticcal and bioanalytical chemistry , 2024, 416 3619-3630.
https://link.springer.com/article/10.1007/s00216-024-05316-7

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Biodegradable SPI-based hydrogel for controlled release of nanomedicines: A potential approach against brain tumors recurrence

Viale, Francesca | Ciprandi, Matilde | Leoni, Luca | Sierri, Giulia | Renda, Antonio | Barbugian, Federica | Koch, Marcus | Sesana, Silvia | Salvioni, Lucia | Colombo, Miriam | Mantegazza, Francesco | Russo, Laura | Re, Francesca

Journal of Drug Delivery Science and Technology , 2024, 96 105672.
https://www.sciencedirect.com/science/article/pii/S1773224724003411

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Targeting Intracellular Bacteria with Dual Drug-loaded Lactoferrin Nanoparticles

Andima, Moses | Boese, Annette | Paul, Pascal | Koch, Marcus | Loretz, Brigitta | Lehr, Claus-Michael

ACS Infectious Diseases , 2024, 10 (5), 1696–1710.
https://pubs.acs.org/doi/full/10.1021/acsinfecdis.4c00045

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Structure–Property Relationships of Granular Hybrid Hydrogels Formed through Polyelectrolyte Complexation

Es Sayed, Julien | Mukherjee, Adrivit | El Aani, Siham | Vengallur, Nayan | Koch, Marcus | Giuntoli, Andrea | Kamperman, Marleen

Macromolecules , 2024, 57 (7), 3190-3201.
https://doi.org/10.1021/acs.macromol.3c02335

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Water-Driven Sol-Gel Transition in Native Cellulose/1-Ethyl-3-methylimidazolium Acetate Solutions

Mohamed Yunus, Roshan Akdar | Koch, Marcus | Dieudonné-George, Philippe | Truzzolillo, Domenico | Colgy, Ralph H. | Parisi, Daniele

ACS Macro Letters , 2024, 13 (2), 219-226.
https://pubs.acs.org/doi/10.1021/acsmacrolett.3c00710

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Data-driven analysis of surface roughness influence on weld quality and defect formation in laser welding of Cu–Al

Norouzian, Mohammadhossein | Elahi, Mahdi Amne | Koch, Marcus | Mahin Zaeem, Reza | Kedziora, Slawomir

Proceedings of the Institution of Mechanical Engineers, Part L: Journal of Materials: Design and Applications , 2024, xxx (xxx), xxx.
https://journals.sagepub.com/doi/10.1177/14644207241236138

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Chitosan/Nanohydroxyapatite/Hydroxyethyl-cellulose-based printable formulations for local alendronate drug delivery in osteoporosis treatment

Afra, Simindokht | Koch, Marcus | Zur-Pinska, Joanna | Dolatshahi, Maryam | Reza Bahrami, Ahmad | Es Sayed, Julien | Moradi, Ali | Matin, Maryam M. | Wlodarczyk-Biegun, Malgorzata K.

2024, 7 100418.
https://www.sciencedirect.com/science/article/pii/S266689392300138X

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Actin-templated Structures: Nature's Way to Hierarchical Surface Patterns (Gecko's Setae as Case Study)

Kasper, Jennifer Y. | Laschke, Matthias W. | Koch, Marcus | Alibardi, Lorenzo | Magin, Thomas M. | Niessen, Carien M. | del Campo, Aránzazu

Advanced Science , 2024, 11 (10), 2303816.
https://onlinelibrary.wiley.com/doi/full/10.1002/advs.202303816

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A cell-free, biomimetic hydrogel based on probiotic membrane vesicles ameliorates wound healing

Kuhn, Thomas | Aljohmani, Ahmad | Frank, Nicolas | Zielke, Lina | Mehanny, Mina | Laschke, Matthias W. | Koch, Marcus | Hoppstädter, Jessica | Kiemer, Alexandra K. | Yildiz, Daniela | Fuhrmann, Gregor

Journal of Controlled Release , 2024, 365 969-980.
https://www.sciencedirect.com/science/article/pii/S0168365923007952

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