Physical Analytics

The service group physical analytics covers electron optical and X-ray analytical investigations for all research departements of INM, research groups of the Saarland University of Saarland and external partners. For nanoscale microscopic investigations, transmission electron (TEM) and scanning electron microscopy (SEM) coupled with X-ray spectral analysis is used. TEM lamellae of a wide variety of samples are prepared inside with a focused ion beam (FIB) microscope and further thinned by focussed Argon ion beam (Nanomill) for atomic analytical analysis. Other preparation techniques such as microtomy, electrolytical polishing, ion milling with non-focusing ion beam and sputter coating are also available.

Aleeza-Farrukh, INM – Leibniz-Institut für Neue Materialien gGmbH
Dr. Marcus Koch
Head of Physical Analytics
Telefon: +49 (0)681-9300-144
Team Members
Phone: +49 (0)681-9300-135
Phone: +49 (0)681-9300-144
Phone: +49 (0)681-9300-247

Publications

2023
Self-Assembly of Polymer-Modified FePt Magnetic Nanoparticles and Block Copolymers

Hartmann, Frank | Bitsch, Martin | Niebuur, Bart-Jan | Koch, Marcus | Kraus, Tobias | Dietz, Christian | Stark, Robert W. | Everett, Christopher R. | Müller-Buschbaum, Peter | Janka, Oliver | Gallei, Markus

Materials , 2023, 16 5503.
https://doi.org/10.3390/ma16165503

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Ageing-associated small RNA cargo of extracellular vesicles

Kern, Fabian | Kuhn, Thomas | Ludwig, Nicole | Simon, Martin | Gröger, Laura | Fabis, Natalie | Aparicio-Puerta, Ernesto | Salhab, Abdulrahman | Fehlmann, Tobias | Hahn, Oiver | Engel, Annika | Wagner, Viktoria | Koch, Marcus | Winek, Katarzyna | Soreq, Hermona | Nazarenko, Irina | Fuhrmann, Gregor | Wyss-Coray, Tony | Meese, Eckart | Keller, Verena | Laschke, Matthias W. | Keller, Andreas

RNA Biology , 2023, 20 (1), 482-494.
https://www.tandfonline.com/doi/full/10.1080/15476286.2023.2234713

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First principles of hydrazine electrooxidation at oxide-free and oxide-based palladium electrodes in complex media

Zolotukhina, E. V. | Butyrskaya, E. V. | Koch, Marcus | Herbeck-Engel, Petra | Levchenko, M.G. | Silina, Yulia E.

Physical Chemistry Chemical Physics , 2023, 25 (14), 9881-9893.
https://doi.org/10.1039/D3CP00829K

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Testing of yeast cells damage using hydrogen peroxide spiking and Pd-NPs-based electrodes and impact of oxidoreductase presence on electrochemical read-out

Koch, Marcus | Katsen-Globa, A. | Zolotukhina, E. V. | Silina, Yulia E.

Biochemical Engineering Journal , 2023, 195
https://www.sciencedirect.com/science/article/abs/pii/S1369703X23001031

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Cell-Derived Vesicles for Antibiotic Delivery—Understanding the Challenges of a Biogenic Carrier System

Heinrich, Eilien | Hartwig, Olga | Walt, Christine | Kardani, Arefeh | Koch, Marcus | Pouralebi Jahromi, Leila | Hoppstädter, Jessica | Kiemer, Alexandra K. | Loretz, Brigitta | Lehr, Claus-Michael | Fuhrmann, Gregor

Small , 2023, 19 (25), 2207479.
https://onlinelibrary.wiley.com/doi/full/10.1002/smll.202207479

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Synthesis and microphase separation of dendrimer-like block copolymers by anionic polymerization strategies

Hartmann, Frank | Niebuur, Bart-Jan | Koch, Marcus | Kraus, Tobias | Gallei, Marcus

European Polymer Journal , 2023, 187
https://www.sciencedirect.com/science/article/abs/pii/S0014305723000770

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A rapid in vitro electrochemical screening of extracellular matrix of Saccharomyces cerevisiae by palladium nanoparticles-modified electrodes

Silina, Yulia E. | Fink-Straube, Claudia | Koch, Marcus | Zolotukhina, E. V.

Bioelectrochemistry , 2023, 149 108283.
https://www.sciencedirect.com/science/article/pii/S1567539422002341

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Proteoid biodynamers for safe mRNA transfection via pH-responsive nanorods enabling endosomal escape

Lee, Sangeun | Nasr, Sarah | Rasheed, Sari | Liu, Yun | Hartwig, Olga | Kaya, Cansu | Boese, Annette | Koch, Marcus | Herrmann, Jennifer | Müller, Rolf | Loretz, Brigitta | Buhler, Eric | Hirsch, Anna K. H. | Lehr, Claus-Michael

Journal of Controlled Release , 2023, 353 915-929.
https://www.sciencedirect.com/science/article/pii/S0168365922008331

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Lipid-Polymer Hybrid Nanoparticles for mRNA Delivery to Dendritic Cells: Impact of Lipid Composition on Performance in Different Media

Kliesch, Lena | Delandre, Simon | Gabelmann, Aljoscha | Koch, Marcus | Schulze, Kai | Guzmán, Carlos A. | Loretz, Brigitta | Lehr, Claus-Michael

Pharmaceutics , 2023, 14 (12), 2675.
https://www.mdpi.com/1999-4923/14/12/2675

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2022
The inherent antibiotic activity of myxobacteria-derived autofluorescent outer membrane vesicles is switched on and off by light stimulation

Lapuhs, Philipp | Heinrich, Eilien | Garcia, Ronald | Goes, Adriely | Frank, Nicolas | Bollenbach, Lukas | Stibane, Veronika | Kuhn, Thomas | Koch, Marcus | Kiemer, Alexandra K. | Müller, Rolf | Fuhrmann, Kathrin | Fuhrmann, Gregor

Nanoscale , 2022, 14 (47), 17534-17542.
http://dx.doi.org/10.1039/D2NR02743G

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