Physical Analytics

The service group physical analytics covers electron optical and X-ray analytical investigations for all research departements of INM, research groups of the Saarland University of Saarland and external partners. For nanoscale microscopic investigations, transmission electron (TEM) and scanning electron microscopy (SEM) coupled with X-ray spectral analysis is used. TEM lamellae of a wide variety of samples are prepared inside with a focused ion beam (FIB) microscope and further thinned by focussed Argon ion beam (Nanomill) for atomic analytical analysis. Other preparation techniques such as microtomy, electrolytical polishing, ion milling with non-focusing ion beam and sputter coating are also available.

Aleeza-Farrukh, INM – Leibniz-Institut für Neue Materialien gGmbH
Dr. Marcus Koch
Head of Physical Analytics
Telefon: +49 (0)681-9300-144
Team Members
Phone: +49 (0)681-9300-135
Phone: +49 (0)681-9300-144
Phone: +49 (0)681-9300-247

Publications

2021
A novel universal algorithm for filament network tracing and cytoskeleton analysis

Flormann, Daniel A. | Schu, Moritz | Terriac, Emmanuel | Thalla, Divyendu G. | Kainka, Lucina | Koch, Marcus | Gad, Annica K. B. | Lautenschläger, Franziska

The FASEB Journal , 2021, 35 (5), e21582.
https://faseb.onlinelibrary.wiley.com/doi/abs/10.1096/fj.202100048R

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One-Pot Synthesis of Copper Iodide-Polypyrrole Nanocomposites

Konakov, Artem O. | Dremova, Nadejda N. | Khodos, Igor I. | Koch, Marcus | Zolotukhina, Ekaterina V. | Silina, Yuliya E.

Chemosensors , 2021, 9 (3), 56.
https://www.mdpi.com/2227-9040/9/3/56

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Micro-Mechanical Response of Ultrafine Grain and Nanocrystalline Tantalum

Yang, Wen | Ruestes, Carlos J. | Li, Zezhou | Abad, Oscar Torrents | Langdon, Terence G. | Heiland, Birgit | Koch, Marcus | Arzt, Eduard | Meyers, Marc A.

Journal of Materials Research and Technology , 2021, 12 1804-1815.
https://www.sciencedirect.com/science/article/pii/S2238785421003070

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A New PqsR Inverse Agonist Potentiates Tobramycin Efficacy to Eradicate Pseudomonas aeruginosa Biofilms

Schütz, Christian | Ho, Duy-Khiet | Hamed, Mostafa Mohamed | Abdelsamie, Ahmed Saad | Röhrig, Teresa | Herr, Christian | Kany, Andreas Martin | Rox, Katharina | Schmelz, Stefan | Siebenbürger, Lorenz | Wirth, Marius | Börger, Carsten | Yahiaoui, Samir | Bals, Robert | Scrima, Andrea | Blankenfeldt, Wulf | Horstmann, Justus Constantin | Christmann, Rebekka | Murgia, Xabier | Koch, Marcus | Berwanger, Aylin | Loretz, Brigitta | Hirsch, Anna Katharina Herta | Hartmann, Rolf Wolfgang | Lehr, Claus-Michael | Empting, Martin

Advanced Science , 2021, 8 (12), 2004369.
https://onlinelibrary.wiley.com/doi/abs/10.1002/advs.202004369

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Visualization of the structure of native human pulmonary mucus

Meziu, Enkeleda | Koch, Marcus | Fleddermann, Jana | Schwarzkopf, K. | Schneider, M. | Kraegeloh, Annette

International Journal of Pharmaceutics , 2021, 597 120238.
https://www.sciencedirect.com/science/article/pii/S0378517321000429

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Stimulation of Probiotic Bacteria Induces Release of Membrane Vesicles with Augmented Anti-inflammatory Activity

Müller, Lisann | Kuhn, Thomas | Koch, Marcus | Fuhrmann, Gregor

ACS Applied Bio Materials , 2021, 4 (5), 3739–3748.
https://doi.org/10.1021/acsabm.0c01136

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Evaluation of the joint based on different surface conditions for aluminum-polyamide laser welding

Elahi, Mahdi Amne | Koch, Marcus | Plapper, Peter

Journal of Laser Applications , 2021, 33 (1), 012036.
https://lia.scitation.org/doi/abs/10.2351/7.0000326

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2020
Tofacitinib loaded squalenyl nanoparticles for targeted follicular delivery in inflammatory skin diseases

Christmann, Rebekka | Ho, Duy-Khiet | Wilzopolski, Jenny | Lee, Sangeun | Koch, Marcus | Loretz, Brigitta | Vogt, Thomas | Bäumer, Wolfgang | Schaefer, Ulrich F. | Lehr, Claus-Michael

Pharmaceutics , 2020, 12 1131-1-17.
https://doi.org/10.3390/pharmaceutics12121131

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Optical detection of di- and triphosphate anions with mixed monolayer-protected gold nanoparticles containing zinc(II)–dipicolylamine complexes

Reinke, Lena | Bartl, Julia | Koch, Marcus | Kubik, Stefan

Beilstein Journal of Organic Chemistry , 2020, 16 2687-2700.
https://dx.doi.org/10.3762/bjoc.16.219

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Synthesis and Biopharmaceutical Characterization of Amphiphilic Squalenyl Derivative Based Versatile Drug Delivery Platform

Ho, Duy-Khiet | Christmann, Rebekka | Murgia, Xabier | De Rossi, Chiara | Frisch, Sarah | Koch, Marcus | Schaefer, Ulrich F. | Loretz, Brigitta | Desmaele, Didier | Couvreur, Patrick | Lehr, Claus-Michael

Frontiers in Chemistry , 2020, 8 (937),
https://www.frontiersin.org/article/10.3389/fchem.2020.584242

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